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SNU Dementia Research Center

Research & Members

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Hye-Sun Kim, Ph.D

Professor
  • Department of Pharmacology
  • Department of Biomedical Sciences
  • Seoul National University, College of Medicine

Contact information

  • Tel

    +82-2-740-8298 (Office)

    +82-2-740-8292 (Lab)

  • E-mail

    hyisun@snu.ac.kr

  • Home page

    Link

Recent Publication (selected)

1. Non-invasive in vivo imaging of caspase-1 activation enables rapid and spatiotemporal detection of acute and chronic inflammatory disorders. Biomaterials. 2020 226:119543. doi: 10.1016/j.

2. Nicotinamide attenuates the decrease in dendritic spine density in hippocampal primary neurons from 5xFAD mice, an Alzheimer's disease animal model. Mol Brain. 2020 13(1):17.

3. Phloroglucinol ameliorates cognitive impairments by reducing the amyloid β peptide burden and pro-inflammatory cytokines in the hippocampus of 5XFAD mice. Free Radic Biol Med. 2018 126:221-234. .

Research Interests

1. Pathogenesis of Alzheimer’s disease

  • Inflammasome activation in Alzheimer’s disease
  • Astrocytes in active state and memory formation

2. Approaches for early diagnosis of Alzheimer’ disease based on detection of inflammasome activation

3. Development of therapeutics for Alzheimer’s disease